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Hidradenitis suppurativa: an update

Ingram, John R. 2016. Hidradenitis suppurativa: an update. Clinical Medicine 16 (1) , pp. 70-73. 10.7861/clinmedicine.16-1-70

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Abstract

Hidradenitis suppurativa (HS) is a chronic, painful skin disease characterised by recurrent inflammatory lesions in flexural locations such as the axillae, groins and perineum. The papules, nodules and abscesses may discharge blood-stained pus which, combined with pain, results in marked quality-of-life reduction. Sinus tracts and scarring may also result. Onset of HS is typically in the second to fourth decades and it affects about 1% of young European adults. There are links with smoking and obesity and an autosomal dominant pattern of inheritance is reported by one-third of patients. Medical management escalates from topical antimicrobials to oral tetracyclines, a combination of clindamycin and rifampicin typically given for 10 weeks, oral disease modifiers, and anti-tumour necrosis factor-alpha therapies. Excision of individual lesions has high recurrence rates which can be minimised by wider excisions, at the expense of longer healing times. Treatment of pain is a relatively neglected aspect of therapy.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Royal College of Physicians
ISSN: 1470-2118
Last Modified: 18 Jun 2019 15:00
URI: http://orca.cf.ac.uk/id/eprint/100504

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