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Cerebral salt wasting following traumatic brain injury

Taylor, Peter, Dehbozorgi, Sasan, Tabasum, Arshiya, Scholz, Anna, Bhatt, Harsh, Stewart, Philippa, Kumar, Pranav, Draman, Mohd S, Watt, Alastair, Rees, Dafydd, Hayhurst, Caroline and Davies, Stephen 2017. Cerebral salt wasting following traumatic brain injury. Endocrinology, Diabetes & Metabolism Case Reports 10.1530/EDM-16-0142

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Abstract

Hyponatraemia is the most commonly encountered electrolyte disturbance in neurological high dependency and intensive care units. Cerebral salt wasting (CSW) is the most elusive and challenging of the causes of hyponatraemia, and it is vital to distinguish it from the more familiar syndrome of inappropriate antidiuretic hormone (SIADH). Managing CSW requires correction of the intravascular volume depletion and hyponatraemia, as well as mitigation of on-going substantial sodium losses. Herein we describe a challenging case of CSW requiring large doses of hypertonic saline and the subsequent substantial benefit with the addition of fludrocortisone.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Neuroscience and Mental Health Research Institute (NMHRI)
Publisher: BioScientifica
ISSN: 2052-0573
Date of First Compliant Deposit: 10 July 2017
Date of Acceptance: 2 March 2017
Last Modified: 07 Dec 2017 15:47
URI: http://orca.cf.ac.uk/id/eprint/102232

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