Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort

Mitchelmore, Philip J., Randall, Joanna, Bull, Matthew, Moore, Karen A., O'Neill, Paul A., Paszkiewicz, Konrad, Mahenthiralingam, Eshwar, Scotton, Chris J., Sheldon, Christopher D., Withers, Nicholas J. and Brown, Alan R. 2018. Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort. Thorax 73 (7) , pp. 677-679. 10.1136/thoraxjnl-2016-209889

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Abstract

While Pseudomonas aeruginosa (PA) cross-infection is well documented among patients with cystic fibrosis (CF), the equivalent risk among patients with non-CF bronchiectasis (NCFB) is unclear, particularly those managed alongside patients with CF. We performed analysis of PA within a single centre that manages an unsegregated NCFB cohort alongside a segregated CF cohort. We found no evidence of cross-infection between the two cohorts or within the segregated CF cohort. However, within the unsegregated NCFB cohort, evidence of cross-infection was found between three (of 46) patients. While we do not presently advocate any change in the management of our NCFB cohort, longitudinal surveillance is clearly warranted.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Publisher:	BMJ Publishing Group
ISSN:	0040-6376
Date of First Compliant Deposit:	16 August 2017
Date of Acceptance:	14 August 2017
Last Modified:	15 Mar 2020 06:02
URI:	http://orca.cf.ac.uk/id/eprint/103655

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