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Severe intellectual disability: systematic review of the prevalence and nature of presentation of unipolar depression

Walton, Catherine and Kerr, Michael 2016. Severe intellectual disability: systematic review of the prevalence and nature of presentation of unipolar depression. Journal of Applied Research in Intellectual Disabilities 29 (5) , pp. 395-408. 10.1111/jar.12203

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Abstract

Background The diagnosis of depression in severe and profound intellectual disability is challenging. Without adequate skills in verbal self-expression, standardized diagnostic criteria cannot be used with confidence. The purpose of this systematic review was to investigate the assessment and diagnosis of unipolar depression in severe and profound intellectual disability. The review aimed to examine the methods used to assess for depression. The secondary aim was to explore the frequency and symptoms of depression. Methods The PRISMA (2009) Checklist for systematic review was followed, and a search of electronic databases was undertaken. Nine studies were included in the qualitative synthesis from over 2000 records identified. Results The quality of the studies was assessed and scored, with a wide range of results. Individual studies scored between 2 and 7 of a maximum possible score of 8. The diagnostic tools utilized by each of the studies were assessed and compared. Conclusions In terms of the methods used to assess for depression, results were varied. This was due to the heterogeneous nature of the individual study designs. The Aberrant Behaviour Checklist consistently showed promise, in particular when combined with other instruments or clinical examination. Qualitative analysis of the selected studies has shown a wide variation in the quality of primary research in this field, with more required to make firm conclusions regarding the diagnosis, frequency and presentation of depression in severe and profound intellectual disability.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Publisher: Wiley
ISSN: 1360-2322
Date of First Compliant Deposit: 5 March 2018
Date of Acceptance: 24 April 2015
Last Modified: 02 Oct 2018 19:31
URI: http://orca.cf.ac.uk/id/eprint/106959

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