Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Lesions in the anterior thalamic nuclei of rats do not disrupt acquisition of stimulus sequence learning

Aggleton, John Patrick, Amin, Eman, Jenkins, Trisha A., Pearce, John Martindale and Ward-Robinson, Jasper 2011. Lesions in the anterior thalamic nuclei of rats do not disrupt acquisition of stimulus sequence learning. The Quarterly Journal of Experimental Psychology 64 (1) , pp. 65-73. 10.1080/17470218.2010.495407

Full text not available from this repository.

Abstract

Sequence learning and spatial alternation were examined in rats with anterior thalamic lesions or sham surgeries. There was a lesion-induced deficit in spatial alternation but not in sequence learning. During sequence learning, rats discriminated between six different sequentially presented compounds (e.g., reinforce A before B, but not B before A), composed of audio-visual elements. The solution required rats to learn both specific stimulus sequences and the reward contingencies associated with these specific temporal relationships. The failure of anterior thalamic lesions to affect the acquisition of this sequential configural task complements the recent finding that anterior thalamic lesions also spare the acquisition of a configural task involving specific stimulus pairings and their spatial relationships. These findings suggest that such “structural” learning is more reliant on cortico-hippocampal than thalamo-hippocampal interactions.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Psychology
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher: Taylor & Francis
ISSN: 1747-0218
Last Modified: 03 Nov 2018 22:56
URI: http://orca.cf.ac.uk/id/eprint/11339

Citation Data

Cited 14 times in Google Scholar. View in Google Scholar

Cited 11 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item