Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Excitotoxic lesions of the rostral thalamic reticular nucleus do not affect the performance of spatial learning and memory tasks in the rat

Wilton, L. A. K., Baird, Alison Lambie, Muir, Janice L. and Aggleton, John Patrick 2001. Excitotoxic lesions of the rostral thalamic reticular nucleus do not affect the performance of spatial learning and memory tasks in the rat. Behavioural Brain Research 120 (2) , pp. 177-187. 10.1016/S0166-4328(00)00369-7

Full text not available from this repository.

Abstract

Rats with cytotoxic lesions of the rostral pole of the thalamic reticular nucleus were compared with surgical control animals on a series of spatial learning and memory tests. While evidence was found for an initial, transient impairment on forced-choice alternation in a T-maze, this rapidly disappeared, and overall performance was unaffected. Subsequent experiments found no evidence that lesions of the rostral reticular nucleus affected the acquisition or performance of tests in the radial arm maze and the Morris water maze. Thus, it appears that the rostral pole of the thalamic reticular nucleus often does not play a necessary role in the performance of tests of spatial learning and memory, in spite of its interconnections with other regions that are required for normal spatial memory.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Psychology
Medicine
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords: Anterior thalamic nuclei; Attention; Rat; Spatial memory; Thalamic reticular nucleus
Publisher: Elsevier
ISSN: 0166-4328
Last Modified: 04 Jun 2017 02:43
URI: http://orca.cf.ac.uk/id/eprint/11399

Citation Data

Cited 5 times in Google Scholar. View in Google Scholar

Cited 5 times in Scopus. View in Scopus. Powered By Scopus® Data

Cited 4 times in Web of Science. View in Web of Science.

Actions (repository staff only)

Edit Item Edit Item