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Lack of effect of dorsomedial thalamic lesions on automated tests of spatial memory in the rat

Neave, N., Sahgal, A. and Aggleton, John Patrick 1993. Lack of effect of dorsomedial thalamic lesions on automated tests of spatial memory in the rat. Behavioural Brain Research 55 (1) , pp. 39-49. 10.1016/0166-4328(93)90005-B

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The effects of cytotoxic lesions of nucleus medialis dorsalis on tests of spatial memory were examined in the rat. Extensive lesions of the nucleus did not impair either the acquisition or the subsequent performance of an automated test of working memory, delayed nonmatchingto- position. Detailed analysis of the animals' performance over varying retention delays failed to reveal any evidence of a deficit. The same animals performed normally in a spatial discrimination task and its subsequent reversals. The present results can be contrasted with those from animals with hippocampal system damage.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords: nucleus medialis dorsalis ; spatial memory ; nonmatching-to-position ; amnesia ; thalamus.
Publisher: Elsevier
ISSN: 0166-4328
Last Modified: 04 Jun 2017 02:43

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