Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Tinea capitis in children: a systematic review of management

Gupta, A. K., Mays, R. R., Versteeg, S. G., Piraccini, B. M., Shear, N. H., Piguet, Vincent, Tosti, A. and Friedlander, S. F. 2018. Tinea capitis in children: a systematic review of management. Journal of the European Academy of Dermatology and Venereology 32 (12) , pp. 2264-2274. 10.1111/jdv.15088

[img]
Preview
PDF - Accepted Post-Print Version
Download (1MB) | Preview

Abstract

Background Tinea capitis is the most common cutaneous fungal infection in children. Objectives This review aims to evaluate the differences that exist between medications for the treatment of tinea capitis, to determine whether there are any significant adverse effects associated and to define the usefulness of sample collection methods. Methods We conducted a systematic literature search of available papers using the databases PubMed, OVID, Cochrane Libraries and ClinicalTrials.gov. Twenty‐one RCTs and 17 CTs were found. Results Among the different antifungal therapies (oral and combination thereof), continuous itraconazole and terbinafine had the highest mycological cure rates (79% and 81%, respectively), griseofulvin and terbinafine had the highest clinical cure rates (46% and 58%, respectively) and griseofulvin and terbinafine had the highest complete cure rate (72% and 92%, respectively). Griseofulvin more effectively treated Microsporum infections; terbinafine and itraconazole more effectively cured Trichophyton infections. Only 1.0% of children had to discontinue medication based on adverse events. T. tonsurans was the most common organism found in North America, and hairbrush collection method is the most efficient method of sample collection. Additionally, using a hairbrush, toothbrush or cotton swab to identify the infecting organism(s) is the least invasive and most efficient method of tinea capitis sample collection in children. Conclusions Current dosing regimens of reported drugs are effective and safe for use in tinea capitis in children.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Blackwell Publishing
ISSN: 0926-9959
Date of First Compliant Deposit: 13 September 2018
Date of Acceptance: 9 May 2018
Last Modified: 29 Jun 2019 08:11
URI: http://orca.cf.ac.uk/id/eprint/114886

Citation Data

Cited 5 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics