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Lazarus Syndrome - Challenges created by pediatric autoresuscitation

Mullen, Stephen, Roberts, Zoe, Tuthill, David, Owens, Laura, Te Water Naude, Johann and Maguire, Sabine 2018. Lazarus Syndrome - Challenges created by pediatric autoresuscitation. Pediatric Emergency Care 10.1097/PEC.0000000000001593

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Abstract

Pediatric autoresuscitation is extremely rare, with only 4 documented cases in the literature. The longest recorded time between stopping cardio pulmonary resuscitation (CPR) and return of spontaneous circulation is 2 minutes. We report a previously well 18-month-old who attended the emergency department after an unexplained cardiac arrest. After 10 cycles of CPR, resuscitation was stopped; 6 minutes later, the patient had a return of spontaneous circulation and was transferred to the pediatric intensive care unit. The patient remains alive but with significant neurological impairment. There are a variety of theories regarding the pathology of pediatric autoresuscitation. The most commonly accepted model is that there is a degree of autopositive end-expiratory pressure impending venous return as a consequence of vigorous ventilation during CPR. This case challenges clinicians to reassess our current definition of death and reaffirms the need for clearer guidelines surrounding the certification of death.

Item Type: Article
Date Type: Published Online
Status: In Press
Schools: Medicine
Publisher: Lippincott, Williams & Wilkins
ISSN: 0749-5161
Date of First Compliant Deposit: 7 March 2019
Date of Acceptance: 1 September 2018
Last Modified: 17 Oct 2019 20:53
URI: http://orca.cf.ac.uk/id/eprint/115498

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