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Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae

Jones, Angharad and Dewitte, Walter 2019. Cell size and cell cycle progression: the cyclin-dependent kinase link in green algae. Journal of Experimental Botany 70 (3) , pp. 731-377. 10.1093/jxb/erz008

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Abstract

The coordination of cell growth and cell division is a fundamental problem in biology. The experiments with unicellular algae of Zachleder et al. (2019) show that up-regulation of cyclin-dependent kinase (CDK) activity can drive cell progression even when biosynthesis is reduced, indicating that the main link between cell growth and cell division is CDK activity rather than overall biosynthesis. Understanding this coupling between cellular growth and CDK activity will be important not just in these algae, but also in higher plants.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Oxford University Press
ISSN: 0022-0957
Date of First Compliant Deposit: 19 February 2019
Date of Acceptance: 8 January 2019
Last Modified: 18 Oct 2019 11:56
URI: http://orca.cf.ac.uk/id/eprint/119701

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