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Controlled delivery of antimicrobial and anti-inflammatory agents from un-cemented prosthesis

Al-Otaibi, Hadil Faris 2019. Controlled delivery of antimicrobial and anti-inflammatory agents from un-cemented prosthesis. PhD Thesis, Cardiff University.
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Abstract

The prevalence of joint replacement procedures has increased by more than 119% in the last decade and as a result the demand for a prosthesis is very likely to increase. Uncemented prosthesis is the first-choice treatment option for patients under 68, due to its long-term and more stable fixation. The two major limitations that lead to the failure of joint replacement surgery are a prosthetic joint infection and aseptic loosening. To counter these limitations this study aimed to develop a novel composite system with dual functionality for prophylaxis from postsurgical inflammation and infection. The system is versatile safe to use in in-vitro.

Item Type: Thesis (PhD)
Date Type: Completion
Status: Unpublished
Schools: Pharmacy
Subjects: R Medicine > RS Pharmacy and materia medica
Date of First Compliant Deposit: 17 July 2019
Last Modified: 16 Jul 2020 02:05
URI: http://orca.cf.ac.uk/id/eprint/124245

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