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Stria terminalis microstructure in humans predicts variability in orienting toward threat

Koller, Kristin, Hatton, Christopher M, Rogers, Robert D and Rafal, Robert D 2019. Stria terminalis microstructure in humans predicts variability in orienting toward threat. European Journal of Neuroscience 50 (11) , pp. 3804-3813. 10.1111/ejn.14504

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Abstract

Current concepts of the extended amygdala posit that basolateral to central amygdala projections mediate fear‐conditioned autonomic alerting, whereas projections to the bed nucleus of the stria terminalis mediate sustained anxiety. Using diffusion tensor imaging tractography in humans, we show that microstructure of the stria terminalis correlates with an orienting bias towards threat in a saccade decision task, providing the first evidence that this circuit supports decisions guiding evaluation of threatening stimuli.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Cardiff University Brain Research Imaging Centre (CUBRIC)
Publisher: Wiley
ISSN: 0953-816X
Date of First Compliant Deposit: 27 August 2019
Date of Acceptance: 29 May 2019
Last Modified: 06 Jul 2020 02:05
URI: http://orca.cf.ac.uk/id/eprint/125121

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