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Whole brain 31P MRSI at 7T with a dual-tuned receive array

Rowland, Benjamin C., Driver, Ian D., Tachrount, Mohamed, Klomp, Dennis W. J., Rivera, Debra, Forner, Ria, Pham, Anh, Italiaander, Michel and Wise, Richard G. 2020. Whole brain 31P MRSI at 7T with a dual-tuned receive array. Magnetic Resonance in Medicine 83 (2) , pp. 765-775. 10.1002/mrm.27953
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Abstract

Purpose: The design and performance of a novel head coil setup for 31P spectroscopy at ultra‐high field strengths (7T) is presented. The described system supports measurements at both the 1H and 31P resonance frequencies. Methods: The novel coil consists of 2, actively detunable, coaxial birdcage coils to give homogeneous transmit, combined with a double resonant 30 channel receive array. This allows for anatomical imaging combined with 31P acquisitions over the whole head, without changing coils or disturbing the subject. A phosphate buffer phantom and 3 healthy volunteers were scanned with a pulse acquire CSI sequence using both the novel array coil and a conventional transceiver birdcage. Four different methods of combining the array channels were compared at 3 different levels of SNR. Results: The novel coil setup delivers significantly increased 31P SNR in the peripheral regions of the brain, reaching up to factor 8, while maintaining comparable performance relative to the birdcage in the center. Conclusions: The new system offers the potential to acquire whole brain 31P MRSI with superior signal relative to the standard options.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Cardiff University Brain Research Imaging Centre (CUBRIC)
Publisher: Wiley
ISSN: 0740-3194
Funders: Wellcome Trust
Date of First Compliant Deposit: 17 September 2019
Date of Acceptance: 26 July 2019
Last Modified: 31 Jan 2020 22:12
URI: http://orca.cf.ac.uk/id/eprint/125510

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