Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

One-pot conversion of allylic alcohols to α-methyl ketones via iron-catalyzed isomerization-methylation

Latham, Daniel E., Polidano, Kurt, Williams, Jonathan M. J. and Morrill, Louis C. 2019. One-pot conversion of allylic alcohols to α-methyl ketones via iron-catalyzed isomerization-methylation. Organic Letters 21 (19) , pp. 7914-7918. 10.1021/acs.orglett.9b02900

[img]
Preview
PDF - Published Version
Available under License Creative Commons Attribution.

Download (1MB) | Preview

Abstract

A one-pot iron-catalyzed conversion of allylic alcohols to α-methyl ketones has been developed. This isomerization–methylation strategy utilized a (cyclopentadienone)iron(0) carbonyl complex as precatalyst and methanol as the C1 source. A diverse range of allylic alcohols undergoes isomerization–methylation to form α-methyl ketones in good isolated yields (up to 84% isolated yield).

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Cardiff Catalysis Institute (CCI)
Publisher: American Chemical Society
ISSN: 1523-7060
Funders: EPSRC
Date of First Compliant Deposit: 24 October 2019
Date of Acceptance: 13 September 2019
Last Modified: 01 Jan 2020 00:29
URI: http://orca.cf.ac.uk/id/eprint/126289

Actions (repository staff only)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics