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Synthesis of a novel macrocyclic lactone system

Smith, Keith, Morris, Ian K. and Bass, Robert J. 1994. Synthesis of a novel macrocyclic lactone system. Heterocycles 37 (3) , pp. 1865-1872. 10.3987/COM-93-S158

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A total synthesis of a 14-membered ring lactone (3) with potential biological activity is described. The final lactonization step uses a modification of the Corey pyidinethiol ester procedure.

Item Type: Article
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: multi-membered O,S-heterocycles (O or S ring members); ring closure reactions
Publisher: Sendai Institute of Heterocyclic Chemistry
ISSN: 0385-5414
Last Modified: 04 Jun 2017 02:51

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