Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Significantly contrasting solid state dynamics of the racemic and enantiomerically pure crystalline forms of an amino acid

Kitchin, Simon J., Tutoveanu, Gianina, Steele, Matthew R., Porter, Elaine L. and Harris, Kenneth David Maclean 2005. Significantly contrasting solid state dynamics of the racemic and enantiomerically pure crystalline forms of an amino acid. Journal of Physical Chemistry B 109 (48) , pp. 22808-22813. 10.1021/jp0532418

Full text not available from this repository.

Abstract

Solid state dynamic properties have been investigated for the racemic (dl) and enantiomerically pure (l) crystalline forms of the amino acid serine [HO·CH2·CH(NH3+)·CO2-] using 2H NMR line shape analysis and 2H NMR spin−lattice relaxation time measurements for samples of dl-serine and l-serine deuterated in the NH3+ and OH groups. 2H NMR line shape analysis indicates that, for both l-serine and dl-serine, the ND3+ group undergoes a 3-site 120° jump motion, with jump frequencies in the intermediate motion regime (103 s-1 to 108 s-1) in the temperature range 153−313 K. However, at a given temperature, the jump frequency is substantially higher for l-serine (e.g., at 233 K, the jump frequency is 5.0 × 106 s-1 for l-serine and 6.0 × 104 s-1 for dl-serine). The OD group is not dynamic on the 2H NMR time scale within the temperature range studied. The results from both 2H NMR line shape analysis (LA) and 2H NMR spin−lattice relaxation time measurements (SLR) indicate that the activation energy for the 3-site 120° jump motion of the ND3+ group is significantly higher for dl-serine [38.0 ± 1.0 kJ mol-1 (LA); 39.7 ± 0.8 kJ mol-1 (SLR)] than for l-serine [23.4 ± 0.8 kJ mol-1 (LA); 23.8 ± 0.3 kJ mol-1 (SLR)]. The difference in activation energies between dl-serine and l-serine is substantially greater than any reported previously for an amino acid in different crystal forms.

Item Type: Article
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: ACS
ISSN: 1520-6106
Last Modified: 04 Jun 2017 02:51
URI: http://orca.cf.ac.uk/id/eprint/12766

Citation Data

Cited 13 times in Google Scholar. View in Google Scholar

Cited 11 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item