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Immunochemical localization of the small leucine-rich proteoglycan lumican in human predentine and dentine.

Hall, R C, Embery, G and Lloyd, D 1997. Immunochemical localization of the small leucine-rich proteoglycan lumican in human predentine and dentine. Archives of Oral Biology 42 (10-11) , 783--786. 10.1016/s0003-9969(97)00024-1

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Abstract

The immunocalization of the small interstitial leucine-rich keratan sulphate proteoglycan lumican was studied in human teeth using a polyclonal antibody towards lumican and a standard indirect peroxidase technique. There was intense labelling for lumican in predentine, with immunopositivity also observed in and around the tubules, around the odontoblasts and in the pulp with a fibrillar distribution. The previous reported ability of lumican to control collagen fibrillogenesis and it putative function in collagen spacing suggest potential roles for lumican in predentine in relation to mineralization.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Elsevier
ISSN: 0003-9969
Date of Acceptance: 4 February 1997
Last Modified: 06 Mar 2020 15:45
URI: http://orca.cf.ac.uk/id/eprint/127839

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