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One or two Ca2+ stores in the neuronal endoplasmic reticulum?

Peng, Shuang and Petersen, Ole H. 2019. One or two Ca2+ stores in the neuronal endoplasmic reticulum? Trends in Neurosciences 42 (11) , pp. 755-757. 10.1016/j.tins.2019.09.003

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Abstract

It is generally accepted that the endoplasmic reticulum (ER) has one continuous lumen and operates as one unified Ca2+ store, but new data from Chen-Engerer et al. in hippocampal neurons now challenge this idea and indicate that receptors for inositol trisphosphate (IP3) and ryanodine may be located in two functionally distinct Ca2+ stores. Are both these stores in the ER?

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Elsevier
ISSN: 0166-2236
Date of Acceptance: 14 October 2019
Last Modified: 31 Aug 2020 15:23
URI: http://orca.cf.ac.uk/id/eprint/129953

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