Imaging biomarkers in neurodegeneration: current and future practices

Young, Peter N. E., Estarellas, Mar, Coomans, Emma, Srikrishna, Meera, Beaumont, Helen, Maass, Anne, Venkataraman, Ashwin V., Lissaman, Rikki, Jiménez, Daniel, Betts, Matthew J., McGlinchey, Eimear, Berron, David, O'Connor, Antoinette, Fox, Nick C., Pereira, Joana B., Jagust, William, Carter, Stephen F., Paterson, Ross W. and Schöll, Michael 2020. Imaging biomarkers in neurodegeneration: current and future practices. Alzheimer's Research and Therapy 12 (1) , 49. 10.1186/s13195-020-00612-7

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Abstract

here is an increasing role for biological markers (biomarkers) in the understanding and diagnosis of neurodegenerative disorders. The application of imaging biomarkers specifically for the in vivo investigation of neurodegenerative disorders has increased substantially over the past decades and continues to provide further benefits both to the diagnosis and understanding of these diseases. This review forms part of a series of articles which stem from the University College London/University of Gothenburg course “Biomarkers in neurodegenerative diseases”. In this review, we focus on neuroimaging, specifically positron emission tomography (PET) and magnetic resonance imaging (MRI), giving an overview of the current established practices clinically and in research as well as new techniques being developed. We will also discuss the use of machine learning (ML) techniques within these fields to provide additional insights to early diagnosis and multimodal analysis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Psychology
Publisher:	BioMed Central
ISSN:	1758-9193
Date of First Compliant Deposit:	28 July 2020
Date of Acceptance:	31 March 2020
Last Modified:	04 May 2023 11:36
URI:	https://orca.cardiff.ac.uk/id/eprint/133841

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