Evaluation of the healthcare resource use and the related financial costs of managing peanut allergy in the United Kingdom

Scott, Laura A., Berni, Thomas R., Berni, Ellen R., De Vries, Jane and Currie, Craig J. 2019. Evaluation of the healthcare resource use and the related financial costs of managing peanut allergy in the United Kingdom. Expert Review of Clinical Immunology 15 (8) , pp. 889-896. 10.1080/1744666X.2019.1641406

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Abstract

Aims: We aimed to estimate the resource use and associated costs for patients with peanut allergy (PA) compared to matched controls. Methods: This was a retrospective cohort study using data from the UK Clinical Practice Research Datalink and Hospital Episode Statistics. PA patients were matched to two control cohorts: the first (simple-matched) were matched 1:1 on year of birth, general practice, gender and registration year. The second (atopy-matched) were matched on the same characteristics plus presence/absence of an atopic condition. Prescriptions and primary and secondary care contacts were compared between cases and controls. Results: 15,483 peanut-allergic patients were identified: 13,609 (87.9%) were simple-matched and 9,320 (60.2%) atopy-matched. The total per person annual incremental health-care costs associated with PA were £253 (atopy-matched) and £333 (simple-matched). For those with PA and a prior anaphylaxis incremental costs were £662, for those prescribed an epinephrine autoinjector incremental costs were £392. Extrapolated to the U.K. population, total excess costs of PA were between £33 and 44 million in 2015. Conclusions: Patients with PA had increased health-care contacts and consequently increased associated costs compared to controls. Observation bias should be considered in interpretation, but this study suggests that PA presents significant burden to health-care systems.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Taylor and Francis
ISSN:	1744-666X
Date of First Compliant Deposit:	4 November 2021
Date of Acceptance:	5 July 2019
Last Modified:	16 Nov 2021 14:15
URI:	https://orca.cardiff.ac.uk/id/eprint/145298

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