Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Highly Selective 5-Substitution of 3-Methylthiophene via Directed Lithiation

Smith, Keith and Barratt, Mark Lewis 2007. Highly Selective 5-Substitution of 3-Methylthiophene via Directed Lithiation. Journal of Organic Chemistry 72 (3) , pp. 1031-1034. 10.1021/jo062024f

Full text not available from this repository.

Abstract

Lithiation of 3-methylthiophene with lithium 2,2,6,6-tetra-methylpiperidide (LiTMP) is highly selective at the 5-position, and reaction with a range of electrophiles gives high yields of the corresponding 2,4-disubstituted thiophenes, even when unhindered electrophiles are used.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: ACS
ISSN: 0022-3263
Last Modified: 04 Jun 2017 01:40
URI: http://orca.cf.ac.uk/id/eprint/1481

Citation Data

Cited 36 times in Google Scholar. View in Google Scholar

Cited 44 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item