Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Biofilms and bacterial imbalances in chronic wounds: Anti-Koch

Percival, S. L., Thomas, John Gilbert and Williams, David Wynne 2010. Biofilms and bacterial imbalances in chronic wounds: Anti-Koch. International Wound Journal 7 (3) , pp. 169-175. 10.1111/j.1742-481X.2010.00668.x

Full text not available from this repository.

Abstract

Microbial imbalances and synergistic relationships between bacteria in medically important biofilms are poorly researched. Consequently, little is known about how synergy between bacteria may increase the net pathogenic effect of a biofilm in many diseases and infections, including chronic wounds. Microbial synergy in chronic wounds may increase virulence and pathogenicity, leading to enhanced tissue degradation, malodour and in some cases, an impairment of the host immune response. Microbial synergy and growth within a biofilm provide a competitive advantage to the microorganisms cohabiting in a wound, thereby promoting their survival and tolerance and resistance to antimicrobial agents. The aim of this article was to provide greater insight into microbial imbalances found within wound biofilms and the significance they may have on non healing and infected wounds. We also present two possible hypotheses which could explain the role microorganisms play in non healing chronic wounds and offer possible strategies for combating harmful and detrimental biofilms. © 2010 Blackwell Publishing Ltd and Medicalhelplines.com Inc.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Dentistry
Uncontrolled Keywords: Bacterial community; Biofilms; Chronic wounds
Publisher: Wiley
ISSN: 1742-481X
Last Modified: 04 Jun 2017 03:03
URI: http://orca.cf.ac.uk/id/eprint/16016

Citation Data

Cited 53 times in Google Scholar. View in Google Scholar

Cited 52 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item