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Adherence and biofilm formation of non-Candida albicans Candida species

Silva, S., Negri, M., Henriques, M., Oliveira, R., Williams, D. W. and Azeredo, J. 2011. Adherence and biofilm formation of non-Candida albicans Candida species. Trends in Microbiology 19 (5) , pp. 241-247. 10.1016/j.tim.2011.02.003

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Abstract

Most cases of candidosis have been attributed to Candida albicans, but recently non- C. albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases and haemolysins). Although 'new' Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of Candida glabrata, Candida parapsilosis and Candida tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity. © 2011 Elsevier Ltd.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Dentistry
Publisher: Elsevier
ISSN: 0966-842X
Last Modified: 04 Jun 2017 03:03
URI: http://orca.cf.ac.uk/id/eprint/16068

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