Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Innate resistance to sporicides and potential failure to decontaminate

Maillard, Jean-Yves ORCID: https://orcid.org/0000-0002-8617-9288 2011. Innate resistance to sporicides and potential failure to decontaminate. Journal of Hospital Infection 77 (3) , pp. 204-209. 10.1016/j.jhin.2010.06.028

Full text not available from this repository.

Abstract

Bacterial spores are frequently intrinsically resistant to biocides and only a number of alkylating and oxidising biocides are sporicidal under certain conditions. Activity against spores is affected by several key factors such as concentration, exposure time, soiling, and the types of surface to be treated. Sporicidal efficacy is usually achieved after an exposure time of several minutes with a high concentration of a biocide. Failure to understand these factors will result in decreased sporicide activity and spore survival. Sporicides in healthcare settings are used for surface disinfection and for the high level disinfection of certain medical devices (e.g. endoscopes). With efficacy data in mind, sporicidal activity should be achieved for the disinfection of medical devices where both high concentration and long exposure time occur. However, for the disinfection of environmental surfaces, high concentration is not recommended, nor is long exposure time achievable. In this case, sporicidal activity is severely reduced and spore survival following treatment is to be expected and contributes to the explanation of spore persistence on surfaces.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Subjects: R Medicine > RB Pathology
R Medicine > RS Pharmacy and materia medica
Uncontrolled Keywords: Clostridium difficile; Disinfection; Endospores; Resistance; Surfaces
Publisher: Elsevier
ISSN: 0195-6701
Last Modified: 18 Oct 2022 14:01
URI: https://orca.cardiff.ac.uk/id/eprint/16181

Citation Data

Cited 52 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item