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Involvement of steroid hormone and growth factor cross-talk in endocrine response in breast cancer

Nicholson, Robert Ian, McClelland, Richard Andrew, Robertson, J. F. R. and Gee, Julia Margeret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 1999. Involvement of steroid hormone and growth factor cross-talk in endocrine response in breast cancer. Endocrine-Related Cancer 6 (3) , pp. 373-387. 10.1677/erc.0.0060373

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Abstract

Multiple lines of evidence implicate steroid hormone and growth factor cross-talk as a modulator of endocrine response in breast cancer and that aberrations in growth factor signaling pathways are a common element in the endocrine resistant phenotype. Delineation of these relationships is thus an important diagnostic goal in cancer research, while the targeting of aberrant growth factor signaling holds the promise of improving therapeutic response rates.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Medicine
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RM Therapeutics. Pharmacology
Publisher: Society for Endocrinology
ISSN: 1351-0088
Last Modified: 18 Oct 2022 14:20
URI: https://orca.cardiff.ac.uk/id/eprint/17165

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