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Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide

Bagley, Mark Christopher and Glover, Christian C. F. 2010. Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide. Molecules 15 (5) , pp. 3211-3227. 10.3390/molecules15053211

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Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: Bohlmann-Rahtz synthesis; cyclization reactions; heterocycles; Lewis acids; pyridines
Publisher: Molecular Diversity Preservation International
ISSN: 1420-3049
Date of First Compliant Deposit: 7 December 2018
Last Modified: 06 Mar 2020 14:59

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