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Efficacy and safety of intranasal xylometazoline and ipratropium in patients with common cold

Graf, P., Eccles, Ronald and Chen, S. 2009. Efficacy and safety of intranasal xylometazoline and ipratropium in patients with common cold. Expert Opinion on Pharmacotherapy 10 (5) , pp. 889-908. 10.1517/14656560902783051

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Background: Many over-the-counter medications are available to treat common cold nasal symptoms, but patients may be unsure which one to use. Methods: This review assesses two widely used intranasal treatments for nasal congestion and rhinorrhea in the common cold: xylometazoline hydrochloride and ipratropium bromide. Results: Xylometazoline quickly and effectively relieves nasal congestion, while ipratropium is effective at reducing rhinorrhea. When used in combination, a novel approach to treatment, nasal congestion and rhinorrhea are treated simultaneously, providing effective relief from two of the most troublesome symptoms of the common cold Both drugs are well tolerated, with only mild to moderate, nasal-related side effects. Conclusions: The efficacy and safety of the combination product suggest that it should be used first-line in the symptomatic relief of nasal congestion and rhinorrhea, before the use of oral treatments.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Subjects: Q Science > Q Science (General)
Uncontrolled Keywords: common cold; ipratropium; nasal congestion; primary care; rhinorrhea; topical nasal spray; xylometazoline
Publisher: Informa Healthcare
ISSN: 1465-6566
Last Modified: 04 Jun 2017 03:44

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