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Ritter reactions in flow

Audiger, Logan Eric, Watts, Kevin, Elmore, Simon C., Robinson, Richard I. and Wirth, Thomas 2012. Ritter reactions in flow. ChemSusChem 5 (2) , pp. 257-260. 10.1002/cssc.201100372

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Ritter reactions are performed in a simple microreactor setup using tert-butylacetate as versatile carbocation source. The protocol avoids the handling of large amounts of hot concentrated sulfuric acid as low concentrations are optimal for rapid access tert-butyl- or diphenylmethyl-protected amides.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: amides; carbocations; medicinal chemistry; microreactors; Ritter reactions
Publisher: Wiley
ISSN: 1864-5631
Last Modified: 04 Jun 2017 03:46

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