Ritter reactions in flow

Audiger, Logan Eric, Watts, Kevin, Elmore, Simon C., Robinson, Richard I. and Wirth, Thomas 2012. Ritter reactions in flow. ChemSusChem 5 (2) , pp. 257-260. 10.1002/cssc.201100372

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Abstract

Ritter reactions are performed in a simple microreactor setup using tert-butylacetate as versatile carbocation source. The protocol avoids the handling of large amounts of hot concentrated sulfuric acid as low concentrations are optimal for rapid access tert-butyl- or diphenylmethyl-protected amides.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
Uncontrolled Keywords:	amides; carbocations; medicinal chemistry; microreactors; Ritter reactions
Publisher:	Wiley
ISSN:	1864-5631
Last Modified:	04 Jun 2017 03:46
URI:	http://orca.cf.ac.uk/id/eprint/26380

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