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Goal-oriented cognitive rehabilitation for an individual with Mild Cognitive Impairment: Behavioural and neuroimaging outcomes

Clare, Linda, van Paasschen, Jorien, Evans, Suzannah J., Parkinson, Caroline, Woods, Robert T. and Linden, David Edmund Johannes 2009. Goal-oriented cognitive rehabilitation for an individual with Mild Cognitive Impairment: Behavioural and neuroimaging outcomes. Neurocase 15 (4) , pp. 318-331. 10.1080/13554790902783116

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Abstract

An individual, goal-oriented cognitive rehabilitation intervention was conducted with AB, a 77-year-old woman with MCI. Outcomes were evaluated using a client-centred measure of goal achievement and an experimental associative learning task testing a skill practised in the intervention. Pre- and post-intervention fMRI scans were compared to examine changes in brain activation. Following intervention, AB showed improved performance on rehabilitation goals and on the associative learning task. There were significant decreases in brain activation in sensory areas and significant increases in memory-related areas. Both client-centred measures and fMRI may assist in detecting clinically-meaningful changes resulting from cognitive rehabilitation interventions.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords: Cognitive plasticity, Cognition-focused intervention, Cognitive training, Goal setting, Memory, fMRI
Publisher: Taylor & Francis
ISSN: 1355-4794
Last Modified: 04 Jun 2017 04:01
URI: http://orca.cf.ac.uk/id/eprint/30853

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