Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

A topography of executive functions and their interactions revealed by functional magnetic resonance imaging

Fassbender, C., Murphy, Kevin, Foxe, J. J., Wylie, G. R., Javitt, D. C., Robertson, I. H. and Garavan, H. 2004. A topography of executive functions and their interactions revealed by functional magnetic resonance imaging. Cognitive Brain Research 20 (2) , pp. 132-143. 10.1016/j.cogbrainres.2004.02.007

Full text not available from this repository.

Abstract

We used fMRI to study the brain processes involved in the executive control of behavior. The Sustained Attention to Response Task (SART), which allows unpredictable and predictable NOGO events to be contrasted, was imaged using a mixed (block and event-related) fMRI design to examine tonic and phasic processes involved in response inhibition, error detection, conflict monitoring and sustained attention. A network of regions, including right ventral prefrontal cortex (PFC), left dorsolateral PFC (DLPFC) and right inferior parietal cortex, was activated for successful unpredictable inhibitions, while rostral anterior cingulate was implicated in error processing and the pre-SMA in conflict monitoring. Furthermore, the pattern of correlations between left dorsolateral PFC, implicated in task-set maintenance, and the pre-SMA were indicative of a tight coupling between prefrontally mediated control and conflict levels monitored more posteriorly. The results reveal that the executive control of behavior can be separated into distinct functions performed by discrete cortical regions.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Physics and Astronomy
Cardiff University Brain Research Imaging Centre (CUBRIC)
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords: Attentional control; Functional MRI; Dorsolateral prefrontal cortex; Anterior cingulate cortex
Publisher: Elsevier
ISSN: 0926-6410
Last Modified: 08 May 2019 14:04
URI: http://orca.cf.ac.uk/id/eprint/33254

Citation Data

Cited 228 times in Google Scholar. View in Google Scholar

Cited 198 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item