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Adhesion of bacteria to stainless steel and silver-coated orthopedic external fixation pins

Wassall, M. A., Santin, M., Isalberti, C., Cannas, M. and Denyer, Stephen Paul 1997. Adhesion of bacteria to stainless steel and silver-coated orthopedic external fixation pins. Journal of Biomedical Materials Research 36 (3) , pp. 325-330. 10.1002/(SICI)1097-4636(19970905)36:3<325::AID-JBM7>3.0.CO;2-G

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Abstract

Bacterial adhesion to silver-coated orthopedic external fixation pins was compared with stainless steel controls in an in vitro study. Using five bacterial isolates from wound infections, the silver coating was found to reduce adhesion for Escherichia coli, Pseudomonas aeruginosa, and two strains of Staphylococcus aureus while the converse applied for Staphylococcus haemolyticus. When placed in human serum, both surfaces were conditioned to a similar extent with serum proteins; this conditioning lead to further reductions in bacterial adhesion, ultimately approaching similar levels for both stainless steel and silver-coated samples.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Subjects: R Medicine > RM Therapeutics. Pharmacology
Publisher: Wiley
ISSN: 1552-4965
Last Modified: 19 Mar 2016 23:14
URI: http://orca.cf.ac.uk/id/eprint/44276

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