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Diagnosing foot infection in diabetes

Williams, D. T., Hilton, Joanna Ruth and Harding, Keith Gordon 2004. Diagnosing foot infection in diabetes. Clinical Infectious Diseases 39 (Supp.2) , S83-S86. 10.1086/383267

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Abstract

Infection represents the presence of an inflammatory response and tissue injury due to the interaction of the host with multiplying bacteria. The disease spectrum is a consequence of the variability in these interactions. Diabetes, because of its effects on the vascular, neurological, and immune systems, can compromise the local and systemic response to infection, potentially masking the typical clinical features and hindering diagnosis. The early recognition of infection, particularly osteomyelitis, is paramount in the management of diabetic foot disease. Careful clinical appraisal remains the cornerstone of the assessment. Hematologic, biochemical, and radiological investigations are important aids in assessing the severity of infection. Microbiological assessment, particularly in more severe infection, requires good-quality samples, combined with rapid transport in an appropriate medium and effective communication with the laboratory. A focused, systematic approach to the accurate diagnosis and treatment of infection, combined with careful monitoring, ensures the maintenance of optimal management.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Additional Information: “You may place your published article in a non-commercial data repository maintained by an institution of which you are a member, provided you meet all relevant conditions described in these Guidelines and in the editorial office’s communications with you. An institutional repository, as distinguished from your personal or departmental web site, is designed for the systematic storage, retrieval, and delivery of scholarly material. Your article may be made publicly available after the appropriate embargo period* [12 months or 3 years for Publications of the Astronomical Society of the Pacific] has been observed. You are responsible for informing the manager of the institutional repository of the embargo period that must be observed. See: http://www.jstor.org/page/publisher/ucpress/rights.html
Publisher: University of Chicago Press
ISSN: 1058-4838
Last Modified: 04 Jun 2017 01:33
URI: http://orca.cf.ac.uk/id/eprint/448

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