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Adenosine-induced respiratory and heart rate changes in young and elderly adults

Watt, A. H., Bayer, Antony James, Routledge, Philip Alexander and Swift, C. G. 1989. Adenosine-induced respiratory and heart rate changes in young and elderly adults. British Journal of Clinical Pharmacology 27 (2) , pp. 265-267. 10.1111/j.1365-2125.1989.tb05360.x

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Abstract

The effects of intravenous boluses of adenosine on respiration and heart rate were compared in young and elderly individuals. Respiratory stimulation and biphasic changes in heart rate were confirmed. The dose-response relationship for the effects of adenosine on respiration and heart-rate did not differ significantly between 10 young (mean age 25.2 + 4.9 years) and 10 elderly (mean age 66 ± 3.1 years) drug-free individuals, indicating that age is unlikely to be a major determinant of adenosine responsiveness.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > RM Therapeutics. Pharmacology
Uncontrolled Keywords: adenosine, age, respiration, heart rate
Publisher: Wiley-Blackwell
ISSN: 0306-5251
Last Modified: 04 Jun 2017 05:14
URI: http://orca.cf.ac.uk/id/eprint/50065

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