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3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria

Amoroso, Angelo James, Arthur, Richard John, Coogan, Michael Peter, Court, Jonathan B., Fernández-Moreira, Vanesa, Hayes, Anthony Joseph, Lloyd, David, Millet, Coralie Ode and Pope, Simon J. A. 2008. 3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria. New Journal of Chemistry 32 (7) , pp. 1097-1102. 10.1039/b802215a

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Abstract

The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by co-localisation studies to accumulate in mitochondria. This represents the first application of a 3MLCT luminescent agent for the specific targeting of a biological entity in imaging.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Biosciences
Publisher: Royal Society of Chemistry
ISSN: 1144-0546
Last Modified: 02 Jan 2018 21:19
URI: http://orca.cf.ac.uk/id/eprint/5842

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