Infant feeding, wheezing, and allergy: a prospective study

Burr, Michael Leslie, Limb, E. S., Maguire, M. J., Amarah, L., Eldridge, B. A, Layzell, J. C. and Merrett, T. G. 1993. Infant feeding, wheezing, and allergy: a prospective study. Archives of Disease in Childhood 68 (6) , pp. 724-728. 10.1136/adc.68.6.724

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Abstract

The determinants of wheezing and allergy were investigated in 453 children with a family history of allergic disease. A randomised controlled trial examined the effects of withholding cows' milk protein during the first three months of life and replacing cows' milk with soya milk. The children were followed up to the age of 7 years. Withholding cows' milk did not reduce the incidence of allergy or wheezing. Children who had ever been breast fed had a lower incidence of wheeze than those who had not (59% and 74% respectively). The effect persisted to age 7 years in the non-atopics only, the risk of wheeze being halved in the breast fed children after allowing for employment status, sex passive smoking, and overcrowding. Allergic disease was not associated with exposure to tobacco smoke, house dust mite antigen, or cats. Breast feeding may confer long term protection against respiratory infection.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Uncontrolled Keywords:	Breast Feeding; Cohort Studies; England / epidemiology; Female; Follow Up Studies; Humans; Hypersensitivity / diettherapy; Hypersensitivity / epidemiology; Hypersensitivity / etiology*; Incidence; Infant; Infant Food; Male; Peak Expiratory Flow Rate; Prevalence; Prospective Studies; Respiratory Sounds / etiology*
Additional Information:	Publication Types Clinical Trial Randomized Controlled Trial Research Support, Non-U.S. Gov't Full Text Sources EBSCO Europe PubMed Central PubMed Central PubMed Central Canada Medical Allergy - MedlinePlus Health Information
Publisher:	BMJ Publishing Group
ISSN:	0003-9888
Last Modified:	04 May 2016 03:04
URI:	https://orca.cardiff.ac.uk/id/eprint/59300

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