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Pyrazolopyridines II: synthesis and antibacterial screening of 6-aryl-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acids

Maqbool, Tahir, Nazeer, Areesha, Khan, Muhammad Naeem, Elliott, Mark Christopher, Khan, Misbahul Ain, Ashraf, Muhammad, Nasrullah, Muhammad, Arshad, Shafia and Munawar, Munawar Ali 2014. Pyrazolopyridines II: synthesis and antibacterial screening of 6-aryl-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acids. Asian Journal of Chemistry 26 (10) , pp. 2870-2872. 10.14233/ajchem.2014.15918

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Abstract

5-Amino-3-methyl-1-phenyl-1H-pyrazole was prepared to react with various aromatic aldehydes and pyruvic acid to afford 6-aryl-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carbxylic acids. The prepared compounds were characterized by Mass, IR, 1H, 13C NMR spectra and CHN analysis data. Various 6-aryl-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carbxylic acids synthesized during this work were also evaluated for their antibacterial activities. Some of these compounds were found to be good antibacterial agents.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: Asian Journal of Chemistry
ISSN: 0970-7077
Last Modified: 18 Feb 2019 11:38
URI: http://orca.cf.ac.uk/id/eprint/59612

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