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Virucidal activity of microbicides

Maillard, Jean Yves, Sattar, Syed A. and Pinto, Federica 2012. Virucidal activity of microbicides. In: Fraise, Adam P., Maillard, Jean Yves and Sattar, Syed A. eds. Russell, Hugo & Ayliffe's: Principles and Practice of Disinfection, Preservation and Sterilization, 5th Edition, Blackwell Publishing, pp. 178-207. (10.1002/9781118425831.ch9)

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Abstract

Viruses are important human pathogens causing substantial mortality and morbidity as well as economic damage. The lack of vaccination strategy and viral resistance to antiviral chemotherapy reemphasize the need for microbicides to eliminate or control viral outbreak. The activity and interactions of microbicides with the viral particle has been far less studied than their effects on bacteria. In addition, differences in virus size and structure as well as the diversity of efficacy test protocols used add to the fragmentation of information and the general lack of understanding of virucides. This chapter is focusing on the use of microbicides to destroy or control the transmission of viruses. The test methodologies are reviewed together with the general virucidal efficacy of different microbicides. Finally, the mechanisms of virucidal action of a number of microbicides are described as well as virus survival to microbicidal exposure.

Item Type: Book Section
Date Type: Publication
Status: Published
Schools: Pharmacy
Subjects: R Medicine > RS Pharmacy and materia medica
Publisher: Blackwell Publishing
ISBN: 9781444333251
Last Modified: 04 Jun 2017 06:29
URI: http://orca.cf.ac.uk/id/eprint/60816

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