Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

DNA polymorphism and the study of disease associations

Cooper, David Neil ORCID: https://orcid.org/0000-0002-8943-8484 and Clayton, John F. 1988. DNA polymorphism and the study of disease associations. Human Genetics 78 (4) , pp. 299-312. 10.1007/BF00291724

Full text not available from this repository.

Abstract

Recombinant DNA approaches to disease analysis may be as applicable to studies of disease association as they are to the analysis and diagnosis of single-gene defects. Population and/or family association analyses, using restriction fragment length polymorphisms around candidate genes as markers, have been employed to study conditions such as atherosclerosis and disease with an HLA-association. Progress made to date in disease-association studies using recombinant DNA methodology is reviewed, the rationale behind such studies is examined and associated problems and pitfalls discussed.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: Springer
ISSN: 0340-6717
Last Modified: 27 Oct 2022 08:21
URI: https://orca.cardiff.ac.uk/id/eprint/62065

Citation Data

Cited 81 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item