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Obstetric variables associated with bipolar affective puerperal psychosis

Robertson Blackmore, Emma, Jones, Ian Richard, Doshi, Monica, Haque, Syeed, Holder, Roger, Brockington, Ian and Craddock, Nicholas John 2006. Obstetric variables associated with bipolar affective puerperal psychosis. British Journal of Psychiatry 188 (1) , pp. 32-36. 10.1192/bjp.188.1.32

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Background Previous cross-sectional studies have highlighted a number of obstetric variables that may be associated with the development of broadly defined puerperal (post-partum) psychosis. These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period. Aims To examine these risk factors in women with well-characterised bipolar affective puerperal psychosis. Method A sample of 129 women with bipolar affective puerperal psychosis were investigated using a design that takes advantage of within-subject comparisons of affected and unaffected deliveries. Results Two of the variables studied were independently associated with an episode of puerperal psychosis: primiparity (odds ratio=3.76, P < 0.001) and delivery complications (odds ratio=2.68, P=0.022). Conclusions This study provides further evidence of the association between primiparity and puerperal psychosis and suggests that complications during delivery may be associated with a severe post-partum episode.

Item Type: Article
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
Publisher: Royal College of Psychiatrists
ISSN: 0007-1250
Last Modified: 04 Jun 2017 06:34

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