Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

The gene for Darier's disease maps between D12S78 and D12S79

Parfitt, E., Burge, S., Craddock, Nicholas John, Roberts, E., McLean, W. H., Weissenbach, J., McGuffin, P. and Owen, Michael John 1994. The gene for Darier's disease maps between D12S78 and D12S79. Human Molecular Genetics 3 (1) , pp. 35-38. 10.1093/hmg/3.1.35

Full text not available from this repository.


Darier's disease is a dominantly inherited skin disorder in which there is abnormal adhesion between keratinocytes. We and others have recently mapped the disease gene to chromosome 12q23-q 24.1. In the present study we have established that the disease gene lies between the loci D12S78 and D12S79 which are 12cM apart. We have also obtained direct evidence that the disease is unlikely to result from a mutation in one of the members of the keratin gene cluster on chromosome 12q.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Publisher: Oxford University Press
ISSN: 0964-6906
Last Modified: 17 Apr 2019 20:59

Citation Data

Cited 29 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item