Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

A feasibility study examining the effect on lung cancer diagnosis of offering a chest X-ray to higher-risk patients with chest symptoms: protocol for a randomized controlled trial

Hurt, Chris Nicholas, Roberts, Kirsty, Rogers, Trevor K, Griffiths, Gareth O., Hood, Kerenza, Prout, Hayley Christine, Nelson, Annmarie, Fitzgibbon, Jim, Barham, Allan, Thomas-Jones, Emma, Edwards, Rhiannon, Yeo, Seow, Hamilton, William, Tod, Angela and Neal, Richard D 2013. A feasibility study examining the effect on lung cancer diagnosis of offering a chest X-ray to higher-risk patients with chest symptoms: protocol for a randomized controlled trial. Trials 14 (1) , 405. 10.1186/1745-6215-14-405

[img]
Preview
PDF - Published Version
Available under License Creative Commons Attribution.

Download (328kB) | Preview

Abstract

Background: In order to improve lung cancer survival in the UK, a greater proportion of resectable cancers must be diagnosed. It is likely that resectability rates would be increased by more timely diagnosis. Aside from screening, the only way of achieving this is to reduce the time to diagnosis in symptomatic cancers. Currently, lung cancers are mainly diagnosed by general practitioners (GPs) using the National Institute for Health and Clinical Excellence (NICE) guidelines for urgent referral for chest X-ray, which recommend urgent imaging or referral for patients who have one of a number of chest symptoms for more than 3 weeks. We are proposing to expand this recommendation to include one of a number of chest symptoms of any duration in higher-risk patients. Methods/Design: We intend to conduct a trial of imaging in these higher-risk patients and compare it with NICE guidelines to see if imaging improves stage at diagnosis and resection rates. This trial would have to be large (and consequently resource-intensive) because most of these patients will not have lung cancer, making optimal design crucial. We are therefore conducting a pilot trial that will ascertain the feasibility of running a full trial and provide key information that will be required in order to design the full trial. Discussion: This trial will assess the feasibility and inform the design of a large, UK-wide, clinical trial of a change to the NICE guidelines for urgent referral for chest X-ray for suspected lung cancer. It utilizes a combination of workshop, health economic, quality of life, qualitative, and quantitative methods in order to fully assess feasibility.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: BioMed Central
ISSN: 1745-6215
Funders: Cancer Research UK, Department of Health, England, ESRC, Health and Social Care Research and Development Division, Public Health Agency, Northern Ireland, National Institute for Social Care and Health Research, Wales, Scottish Government
Date of First Compliant Deposit: 30 March 2016
Last Modified: 05 Jun 2019 01:56
URI: http://orca.cf.ac.uk/id/eprint/63826

Citation Data

Cited 5 times in Google Scholar. View in Google Scholar

Cited 6 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics