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Highly sensitive detection of fungal antigens by ultrasound-enhanced latex agglutination

Grundy, M. A., Barnes, Rosemary Ann and Coakley, W. T. 1995. Highly sensitive detection of fungal antigens by ultrasound-enhanced latex agglutination. Journal of Medical and Veterinary Mycology 33 (3) , pp. 201-203. 10.1080/02681219580000411

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Treatment with ultrasound has been employed to greatly enhance the sensitivity of commercially available latex agglutination tests for fungal antigens. This 5 min procedure detects 40 pg ml-1 of Candida albicans mannan and 70 pg ml-1 of Aspergillus fumigatus galactomannan, a 250 and 500-fold improvement respectively over conventional agglutination test sensitivities. The ultrasound-enhanced test offers the possibility of improved diagnosis and management of patients with systemical candidosis or invasive aspergillosis.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: Informa Plc.
ISSN: 1369-3786
Last Modified: 04 Jun 2017 07:43

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