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Invasive pulmonary aspergillosis in non-immunocompromised patients

Hovenden, J. L., Nicklason, F. and Barnes, Rosemary Ann 1991. Invasive pulmonary aspergillosis in non-immunocompromised patients. British Medical Journal (BMJ) 302 (6776) , pp. 583-584. 10.1136/bmj.302.6776.583

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Profound neutropenia is the most common predisposing feature in invasive aspergillosis.' Classically, patients receiving cytotoxic chemotherapy for acute haematological malignancy, recipients of organ transplants, and those on high doses of systemic corticosteroids are most at risk. Chronic granulomatous disease, alcoholism, influenza, diabetes, and parenteral antibiotics have also occasionally been implicated as predisposing factors. 6 Invasive aspergillosis is- very rare outside these groups. We report on two patients with fatal pulmonary aspergillosis in whom early suspicion and invasive diagnostic procedures may have affected outcome.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: BMJ Publishing Group
ISSN: 0959-8138
Last Modified: 04 Jun 2017 07:44

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