Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

lkB kinase alpha: a link in the chain of the mammary cycle

Clarkson, Richard W. E. 2002. lkB kinase alpha: a link in the chain of the mammary cycle. Breast Cancer Research 4 , 173. 10.1186/bcr446

Full text not available from this repository.

Abstract

The transcription factor NF-κB exhibits altered activity in some breast cancers but the relevance of this association has not been established. Cao et al.'s elegant study recently published in Cell reveals a NF-κB-dependent signalling pathway responsible for epithelial proliferation in the mouse mammary gland. Could this mechanism, rather than prevention of apoptosis, be responsible for the reported association between NF-κB and breast cancer? Could the specificity of NF-κB modulators of the IkB kinase complex determine the fate of epithelial cells at different stages of mammary development?

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
European Cancer Stem Cell Research Institute (ECSCRI)
Uncontrolled Keywords: Apoptosis; IkB kinase; mammary; NF-κB; proliferation.
Publisher: BioMed Central
ISSN: 1465-5411
Last Modified: 04 Jun 2017 07:58
URI: http://orca.cf.ac.uk/id/eprint/70984

Citation Data

Cited 3 times in Scopus. View in Scopus. Powered By Scopus® Data

Cited 2 times in Web of Science. View in Web of Science.

Actions (repository staff only)

Edit Item Edit Item