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Neural tube malformations and trace elements in water

Leger, A. S., Elwood, Peter Creighton and Morton, M. S. 1980. Neural tube malformations and trace elements in water. Journal of Epidemiology & Community Health 34 (3) , pp. 186-187. 10.1136/jech.34.3.186

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A retrospective case-control study was conducted to test the hypothesis that there is an association between the trace element content of domestic tap water and neural tube malformations in infants. Of 11 elements examined a notable difference was found only for zinc, this being lower in the cases than in the controls. This difference, however, was small and when allowance is made for the total number of statistical comparisons it is compatible with chance fluctuation. From the results of this study, together with the inconsistency of the literature as a whole, it is concluded that trace elements in tap water are unlikely to be of relevance to congenital malformations.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: BMJ Publishing
ISSN: 0143-005x
Last Modified: 04 Jun 2017 07:59

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