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Comparison between halothane and sevoflurane for adult vital capacity induction

Hall, Judith Elizabeth, Oldham, T. A., Stewart, J. I. and Harmer, M. 1997. Comparison between halothane and sevoflurane for adult vital capacity induction. British Journal of Anaesthesia 79 (3) , pp. 285-288. 10.1093/bja/79.3.285

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Abstract

We have examined the differences in ventilatory characteristics between halothane and sevoflurane when used for adult vital capacity induction of anaesthesia. The study was conducted in a randomized, double-blind manner. After 13 patients had been enrolled, the study was curtailed because the blinded observer thought that there was an unacceptably high incidence of adverse events. After the randomization code was revealed, the adverse events were found to be in the halothane group. Although the sample size was small, minute volumes appeared to be maintained in the sevoflurane group. Ventilatory frequencies were similar in the two groups after insertion of the laryngeal mask airway, but tidal volumes were significantly greater in the sevoflurane group (P = 0.0013).

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Publisher: Oxford University Press
ISSN: 0007-0912
Last Modified: 04 Jun 2017 08:00
URI: http://orca.cf.ac.uk/id/eprint/71500

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