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Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period

Jones, Ian Richard, Chandra, Prabha S., Dazzan, Paola and Howard, Louise M. 2014. Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period. Lancet 384 (9956) , pp. 1789-1799. 10.1016/S0140-6736(14)61278-2

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Abstract

The perinatal period is associated with an increased risk of severe mental disorders. We summarise the evidence regarding the epidemiology, risk factors, and treatment of severe mental illness in relation to childbirth, focusing on bipolar disorder, affective psychosis, and schizophrenia. We discuss women with ongoing chronic conditions and those with the onset of new episodes of post-partum psychosis. Despite the importance of perinatal episodes, with suicide a leading cause of maternal death, few studies are available to guide the management of women with severe mental disorders in pregnancy and the post-partum period. However, general principles of management are discussed, including the need for an individual risk-benefit analysis for each woman.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
Publisher: Elsevier: Lancet
ISSN: 0140-6736
Last Modified: 14 Mar 2019 11:21
URI: http://orca.cf.ac.uk/id/eprint/74803

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