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A comparison of hyperelastic constitutive models applicable to brain and fat tissues

Mihai, Loredana Angela, Chin, LiKang, Janmey, Paul A. and Goriely, Alain 2015. A comparison of hyperelastic constitutive models applicable to brain and fat tissues. Journal of the Royal Society Interface 12 (10) , pp. 1-12. 10.1098/rsif.2015.0486

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Abstract

In some soft biological structures such as brain and fat tissues, strong experimental evidence suggests that the shear modulus increases significantly under increasing compressive strain, but not under tensile strain, while the apparent Young’s elastic modulus increases or remains almost constant when compressive strain increases. These tissues also exhibit a predominantly isotropic, incompressible behaviour. Our aim is to capture these seemingly contradictory mechanical behaviours, both qualitatively and quantitatively, within the framework of finite elasticity, by modelling a soft tissue as a homogeneous, isotropic, incompressible, hyperelastic material and comparing our results with available experimental data. Our analysis reveals that Fung and Gent models, which are typically used to model soft tissues, are inadequate for the modelling of brain or fat under combined stretch and shear, and so are the classical neo-Hookean and Mooney-Rivlin models used for elastomers. However, a sub-class of Ogden hyperelastic models are found to be in excellent agreement with the experiments. Our findings provide explicit models suitable for integration in large-scale finite element computations.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Mathematics
Subjects: Q Science > QA Mathematics
Publisher: The Royal Society
Funders: EPSRC
Date of First Compliant Deposit: 30 March 2016
Date of Acceptance: 20 August 2015
Last Modified: 03 Jul 2019 10:27
URI: http://orca.cf.ac.uk/id/eprint/75937

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