Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Exploratory randomized trial on the effect of a brief psychological intervention on emotions, quality of life, discontinuation, and pregnancy rates in in vitro fertilization patients

Domar, Alice D., Gross, Jill, Rooney, Kristin and Boivin, Jacky 2015. Exploratory randomized trial on the effect of a brief psychological intervention on emotions, quality of life, discontinuation, and pregnancy rates in in vitro fertilization patients. Fertility and Sterility 104 (2) , pp. 440-451. 10.1016/j.fertnstert.2015.05.009

Full text not available from this repository.

Abstract

Objective To determine whether a brief self-administered cognitive coping and relaxation intervention (CCRI) would lead to decreased treatment termination in in vitro fertilization (IVF) patients compared with routine care (RC). Design Randomized, controlled, prospective study. Setting Private academically affiliated infertility center. Patient(s) One hundred sixty-six women about to begin their first IVF cycle. Intervention(s) Randomization to the self-administered CCRI or RC control group and then observation for 12 months. Main Outcome Measure(s) Treatment discontinuation within 12 months (primary outcome), clinical pregnancy rate and psychological well-being (secondary outcomes). Result(s) The 12-month pregnancy rate was similar for the RC and CCRI groups (odds ratio [OR] 1.02; 95% CI, 0.53–1.98). Of the patients who were not pregnant on the first cycle, 15 of 46 (15.2%) patients assigned to RC discontinued compared with 5 of 55 (5.5%) patients assigned to the CCRI (OR 3.11; 95% CI, 0.756–12.80). The CCRI group engaged in statistically significantly more positive reappraisal coping (OR 0.275; 95% CI, 0.16, 0.39) than the RC control group (OR 0.097; 95% CI, −0.03, .23). The CCRI group had an improved Fertility Quality of Life (FertiQoL CORE: OR 4.07; 95% CI, 2.07, 6.06; FertiQoL Emotional: OR 5.95; 95% CI, 2.89, 9.00) compared with the control group (Core OR: 0.67; 95% CI, −1.55, 2.89; Emotional: OR −0.02, 95% CI, −3.36, 3.32). The CCRI group reported less global anxiety (OR 0.275; 95% CI, 0.16, 0.39) than the control group (OR 0.471; 95% CI, −2.40, 3.34). The CCRI reported positive evaluations for the intervention (e.g., ease of use, helpfulness, perceived stress reduction). Conclusion(s) Use of the CCRI tool led to improved psychological status but not statistically significantly more treatment cycles or a higher pregnancy rate.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Additional Information: Available online 13 June 2015
Publisher: Elsevier
ISSN: 0015-0282
Date of Acceptance: 8 May 2015
Last Modified: 06 Mar 2019 14:50
URI: http://orca.cf.ac.uk/id/eprint/75963

Citation Data

Cited 20 times in Google Scholar. View in Google Scholar

Cited 31 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item