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Tackling cell transplantation anoikis: an injectable, shape memory cryogel microcarrier platform material for stem cell and neuronal cell growth

Newland, Benjamin, Welzel, Petra B., Newland, Heike, Renneberg, Claudia, Kolar, Petr, Tsurkan, Mikhail, Rosser, Anne Elizabeth, Freudenberg, Uwe and Werner, Carsten 2015. Tackling cell transplantation anoikis: an injectable, shape memory cryogel microcarrier platform material for stem cell and neuronal cell growth. Small 11 (38) , pp. 5047-5053. 10.1002/smll.201500898

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Abstract

Highly macroporous semisynthetic cryogel microcarriers can be synthesized for culturing stem cells and neuronal type cells. Growth factors loaded to heparin-containing microcarriers show near zero-order release kinetics and cell-loaded microcarriers can be injected through a fine gauge cannula without negative effect on the cells. These carriers can be applied for cell transplantation applications.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Medicine
Neuroscience and Mental Health Research Institute (NMHRI)
Pharmacy
Uncontrolled Keywords: adherent matrix; biomaterials; heparin; neurotrophin; star-PEG; shape memory; cryogels; microcarriers.
Publisher: Wiley
ISSN: 1613-6810
Date of First Compliant Deposit: 1 November 2017
Last Modified: 15 Dec 2017 16:17
URI: http://orca.cf.ac.uk/id/eprint/76275

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